Skip to main content
NameEmailPhD ProgramResearch InterestPublications
Giri, Gilbert

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genetics

Merker, Jason
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Pathobiology & Translational Science

RESEARCH INTEREST
Bioinformatics, Cancer Biology, Genomics, Pharmacology, Translational Medicine

Our laboratory is focused on translating novel molecular biomarkers into clinical oncology practice, with the overarching goal of improving the care and survival of patients with cancer. Our group is highly collaborative and applies genomic, genetic, bioinformatic, informatic, statistical, and molecular approaches. Current projects in the laboratory include:

  1. Correlative genomic testing to support clinical trials
  2. Expanded clinical applications of RNA sequencing
  3. Development and application of cell-free circulating tumor nucleic acid assays
Ramos, Silvia
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Biochemistry & Biophysics

RESEARCH INTEREST
Biochemistry, Bioinformatics, Molecular Biology, Pathology, Translational Medicine

Our research is focused on RNA-binding proteins and their physiopathological roles. An understudied aspect of human disease is gene regulation by modulation of mRNA function. In our research lab we investigate functional connections between the RNA-binding protein Zinc Finger Protein 36 Like-2 (ZFP36L2 or L2) and human diseases. L2 is a member of the Tris-Tetra-Proline or Zinc Finger Protein 36 (TTP/ZFP36) family of RNA-binding proteins that bind Adenine-uridine-Rich Elements (AREs) in the 3’ untranslated regions of target mRNAs. Upon binding, L2 accelerates mRNA target degradation and/or inhibits mRNA translation, ultimately decreasing the protein encoded by the L2-target mRNA.

We have three particular goals:

  • Determine new specific L2-mRNA targets involved in human diseases.
  • Determine the mechanism(s) by which L2 modulates these novel RNA targets.
  • Determine the physiological consequences of L2 ablation in specific cells types using mouse models and CRISPR/Cas9-mediated knockout system.
Alkhawaja, Abdalla

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genomics

Byun, Jess

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genomics

Eberhard, Quinn

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Structural Biology

Flores, JP

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Biochemistry, Bioinformatics, Epigenetics, Genetics

Forbes, Kwame

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genetics

Kent, Leslie

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bacteriology, Bioinformatics, Pathology

Lee, Andy

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Cancer Genomics, Computational Biology, Genetics