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NameEmailPhD ProgramResearch InterestPublications
Raffield, Laura
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Bioinformatics & Computational Biology

RESEARCH INTEREST
Genetics, Genomics

Keywords: genetic epidemiology, human genetics, genome-wide association studies, precision medicine, multi-omics, cardiovascular disease, inflammation, hematological traits

In my research program, I use human genomics and multi-omics to understand inherited and environmental risk factors for cardiometabolic diseases and related quantitative traits. I work to link genetic variants to function through integration with multi-omics data, including transcriptomic, methylation, proteomic, and metabolomic measures. This work has important implications for cardiometabolic risk prediction across diverse populations and improved understanding of disease biology. A focus on understudied African American and Hispanic/Latino populations is a central theme of my research; human genetics research is dramatically unrepresentative of global populations, with ~95% of genome-wide association study participants of European or East Asian ancestry. As complex trait genetics moves into the clinic, increasing diversity is essential to ensure that all populations benefit from the promise of precision medicine.

I play a leadership role in collaborative efforts in human genetics, for example serving as a Genetics Working Group co-chair for the Jackson Heart Study (JHS), one of the largest population based studies of African Americans, and an Inflammation/Hematology working group co-chair for the Population Architecture Using Genomics and Epidemiology (PAGE) consortium. I am also a co-convener of the Multi-Omics working group for the NHLBI Trans-Omics for Precision Medicine (TOPMed) program.

Miller, Brian
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Cell Biology & Physiology, Genetics & Molecular Biology

RESEARCH INTEREST
Cancer Biology, Genetics, Immunology, Systems Biology, Translational Medicine

The Miller lab is working to improve the efficacy of immunotherapy to treat cancer. We aim to develop personalized immunotherapy approaches based on a patient’s unique cancer mutations. We have a particular interest in myeloid cells, a poorly understood group of innate immune cells that regulate nearly all aspects of the immune response. Using patient samples, mouse models, single-cell profiling, and functional genomics approaches, we are working to identify novel myeloid-directed therapies that allow us to overcome resistance and successfully treat more patients.

Lin, Jessica
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Microbiology & Immunology

RESEARCH INTEREST
Genetics, Genomics, Molecular Biology, Molecular Medicine, Pathogenesis & Infection

Dr. Lin is an infectious disease physician-scientist whose research lies at the interface of clinical and molecular studies on malaria. My current projects focus on 1) determinants of malaria transmission from human hosts to mosquitos and 2) the epidemiology and relapse patterns of Plasmodium ovale in East Africa. Work in my lab involves applying molecular tools (real-time PCR, amplicon deep sequencing, whole genome sequencing, and to a lesser extent antigen and antibody assays) to samples collected in clinical field studies to learn about malaria epidemiology, transmission, and pathogenesis.

Giri, Gilbert

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genetics

Coelho, Jenny

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Genetics, Immunology, Translational Medicine

Boyson, Sam

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Genetics, Genomics, Molecular Biology

DiBattista, Anna

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Genetics, Molecular Biology, Plant Biology

Edwards, Alyssa

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Genetics, Molecular Biology, Translational Medicine

Flores, JP

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Biochemistry, Bioinformatics, Epigenetics, Genetics

Forbes, Kwame

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bioinformatics, Computational Biology, Genetics