Young, Sam
WEBSITE
EMAIL PUBLICATIONS |
PHD PROGRAM Genetics & Molecular Biology, Pharmacology RESEARCH INTEREST Biophysics, Cell Biology, Gene Therapy, Molecular Medicine, Neurobiology, Pharmacology, Physiology, Virology
|
My research is focuses on two general areas: 1) Molecular principles of auditory information processing, and 2) Gene Therapy approaches to treat neurological disorders. In regard to our auditory focus, we seek to understand how the molecular machinery in auditory brainstem synapses enables neuronal computations at some of the fastest speeds in the central nervous system to enable the ability to identify and interpret sound information received by the ears. In regard to our gene therapy approaches, we seek to develop novel viral vector technology to create novel therapeutic strategies to treat neuronal dysfunction and degeneration to improve the quality of life of individuals who suffer from neurological diseases. To address these research areas, I employ a multi-disciplinary strategy that encompasses, molecular biology, virology, viral vectors, biophysics, light microscopy, electron microscopy, electrophysiology, and transgenic mouse models.
Keywords: Gene therapy, synaptic transmission, Hearing, viral vectors, biophysics, ion channels, calcium signaling, neurodegeneration, molecular medicine, synaptic plasticity, molecular engineering, nanomedicine
|
Hsueh, Ming-Feng
WEBSITE
EMAIL PUBLICATIONS |
PHD PROGRAM Cell Biology & Physiology RESEARCH INTEREST Arthritis, Cell Biology, Gene Therapy, Molecular Mechanisms of Disease, RNA Biology, Regenerative Medicine, Translational Medicine
|
Dr. Hsueh’s research is at the forefront of translational musculoskeletal and aging biology, utilizing cutting-edge multi-omic technologies to pioneer new therapeutic strategies for regenerating damaged joint tissue, with a particular focus on osteoarthritis (OA). Our lab employs advanced in vitro cell culture and cartilage explant models to delve into the mechanisms driving OA pathogenesis and to evaluate the potential of novel drug therapies. A key area of our research investigates the role of noncoding RNAs in human musculoskeletal tissues. We aim to uncover the intricate signaling pathways and downstream gene networks influenced by these noncoding RNAs. Our ultimate goal is to harness this knowledge to enhance the body’s natural repair mechanisms, providing innovative solutions to combat the progression of OA and restore joint function
|
Travis, Kanesha
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cell Biology, Metabolism, Molecular Biology
|
“I have no definitive areas of research I want to focus on specifically. I would like to do research looking at disease models in either disease/obesity or neurodegenerative disorders, but I am more of an open slate at this stage.”
|
Smith, Audrey
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Behavior, Cell Biology, Neurobiology
|
“I am interested in neuroscience research that delves into the molecular mechanisms underlying psychiatric disorders, addiction, and neurodevelopmental disorders. I am particularly interested in how stressors affect the progression of these mechanisms.”
|
Sadritabrizi, Taraneh
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cell Biology, Immunology, Toxicology
|
“I am interested in basic and translational research on the pathogenesis of lung injury and disease. I also look forward to exploring modifiers of disease and the immune response to inhalation exposures.”
|
Sadovsky, Matheus
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cell Biology, Cell Signaling, Developmental Biology
|
“I am interested in research questions involving cell and developmental biology; specifically, understanding how signaling pathways drive cell fate and contribute to the structure and function of an organ system. Because several human diseases arise from malfunctions of cellular mechanisms, research in this area is important for expanding our understanding of cells and designing targeted treatments.”
|
Rowland, Violet
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cancer Biology, Cell Biology
|
“I am interested in understanding how cancer develops and evolves depending on its environment. I am particularly interested in trying to understand why certain subpopulations in a tumor become metastatic or resistant to therapy, with the ultimate goal of creating treatments that can better help those affected by cancer.”
|
Pon, Ailing
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Biochemistry, Cell Biology, Chemical Biology
|
“I have a keen interest in epigenetics, particularly its implications for cancer research. Additionally, I am passionate about developing chemical probes to explore the field of epigenetics.”
|
Norton, Jenna
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cell Biology, Developmental Biology, Genetics
|
“My research experience has ranged from tropical ecology to identifying downstream effectors of collective cell migration, so, my interests are very broad. I am excited about how cells change shape and move and how this affects the whole animal. I am looking forward to learning more about how cells communicate with each other and furthering my scientific journey.”
|
McCarthy, Ben
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST Cell Biology, Genetics, Molecular Biology
|
“I am interested in understanding the function of genes by studying the molecular interactions of their gene products and how these contribute to cellular and organismal health. I am also interested in mechanisms of gene regulation the dynamics of gene expression in response to internal and environmental cues. How genotype and phenotype are connected, and how gene expression responds to changes in the environment are broadly what I want to study. I would like to focus on discovering novel molecular mechanisms and ways of thinking about these basic biology concepts.”
|