Vetreno, Ryan
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PHD PROGRAM Neuroscience, Pharmacology RESEARCH INTEREST Addiction/Alcohol Research, Aging/Alzheimer's, Behavior, Biochemistry, Brain Development, Developmental Biology, Disease, Epigenetics & Chromatin Biology, Immunology, Microbiome, Molecular Biology, Molecular Mechanisms of Disease, Neurobiology, Neurodevelopmental Disorders, Neuropharmacology, Pathology, Pharmacology, Regenerative Medicine
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My research interests involve investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) alcohol responsivity and tolerance, (3) adolescent neurodevelopment, (4) cholinergic system and neurocircuitry, (5) microglial function, and (6) Alzheimer’s disease. A major focus of the laboratory is elucidation of neuroimmune and epigenetic mechanisms underlying adolescent binge alcohol-induced disruption of basal forebrain cholinergic neurocircuitry in adulthood. A second major focus of the laboratory is investigation of lasting adolescent binge drinking-induced neuroimmune priming as a novel etiological factor contributing to the onset and progression of basal forebrain neuropathology in Alzheimer’s disease. Our laboratory combines ex vivo and in vivo rodent models of alcohol abuse and Alzheimer’s disease with innovative molecular techniques.
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Duprey, Kelsey
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Genetics, Molecular Biology
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“I am interested in DNA repair and replication, cell cycle and chromosome segregation, epigenetics, and developmental biology. I am looking to work with Drosophila, C. elegans, zebrafish, or cell cultures.”
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Bingham, Johnna
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Drug Discovery, Molecular Biology
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“I’m interested in doing research at the intersection of where chemistry and biology meet and using discovery to improve the lives and health of others.”
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Gringeri, Abby
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Biomaterials, Developmental Biology
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“I am generally interested in developing biomaterials, particularly in the context of tissue engineering. This includes hydrogel tissue scaffolds, microfluidic devices, etc. I am also interested in the chemistry of polymeric materials used for these applications.”
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Simmons, Jake
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Biophysics, Molecular Biology
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“I find myself loving molecular biology techniques, but I always come back to asking how the chemistry works. For this reason, I maintain a great openness in where I land in my rotations, however, I am confident any sort of mechanistic approach will fill my curiosity. Anywhere between protein and cells, interests me. Biochemistry or molecular biology is where I see myself thriving. Particularly, I recently developed an interest in Cryo-EM, however, I’ll admit I have never researched using it.”
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Hawkins, Aspen
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Pharmacology
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“My research interests lie at the intersection of biochemistry and pharmacology. I am specifically interested in understanding the cellular and molecular mechanisms of disease so that better therapeutics can be developed to target those diseases.”
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Do, Jamie
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Biophysics, Chemical Biology
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“Building on my previous research experience in thiol redox chemistry, enzymology, and protein design, I am eager to delve deeper into the field of macromolecular structure and dynamics as well as chemical biology. For instance, I want to investigate the conformational changes of macromolecules and develop novel small molecule inhibitors for targeted drug delivery. From my current knowledge, the Biochemistry and Biophysics and Pharmaceutical Sciences programs within BBSP will provide the ideal environment for pursuing these research interests. I am also excited about the opportunity to rotate in a lab whose research focus is beyond what I have mentioned.”
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Reist, Claire
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Immunology, Translational Medicine
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“I am interested in translational research with a biochemistry/molecular biological approach to understanding mechanisms of disease and identification of potential therapeutic approaches toward treatment. My previous work has focused on airway infection of Cystic Fibrosis and other respiratory diseases. I would like to continue working in a lab whose focus is producing applicable results that directly benefit human health and accelerate the movement of scientific discoveries into clinical practice.”
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Jimenez, Alli
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Biophysics, Physiology
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“I am interested in using biochemistry and biophysics to investigate mechanisms underlying certain disease states. In particular, I find the mechanics of protein folding and dynamics to be very intriguing.”
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Fisher, Caleb
EMAIL
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PHD PROGRAM
RESEARCH INTEREST Biochemistry, Bioinformatics, Structural Biology
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“Broadly, I have an interest in studying enzymology and structural biology to answer questions related to immune and metabolism diseases such as cancer. I think that advancing our understanding of such diseases requires structure-function studies of large protein families, such as GPCRS, to be driven by bioinformatics paired with fundamental biochemistry. A particular question I’m curious about is how the structure of such enzymes contribute to the big-picture of cellular dynamics? More specifically, how does regulation of enzymes change their structural dynamics and how does this fit into the big-picture phenomena of disease?”
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