Research Interest: Translational Medicine

PHD PROGRAM
Microbiology & Immunology

RESEARCH INTEREST
Pathogenesis & Infection, Pulmonary Research, Respiratory Physiology & Infections, Translational Medicine

The Livraghi-Butrico lab is focused on exploring the key determinants of effective airway mucus clearance in health, as well as the consequences of its derangement in muco-obstructive lung diseases. Our lab leverages the unparalleled functional integration offered by in vivo animal models to test mechanistic hypotheses and vet therapeutic options for pre-clinical development.

PHD PROGRAM
Pharmaceutical Sciences

RESEARCH INTEREST
Chemical Biology, Drug Discovery, Translational Medicine

We are inspired by the diversity and complexity found in natural products and use their architecture as both a platform for developing chemical methods and as scaffolds for new molecular tools in chemical biology. We have employed our chemical synthesis skill set to solve emerging challenges facing modern medicine. This has led to ongoing collaborative projects in metastatic cancer, hepatitis C antivirals, dopamine signaling and sigma receptor ligands. Of particular interest is the development of next generation anti-metastasis agents to our recent phase I clinical candidate, metarrestin.

PHD PROGRAM
Pharmaceutical Sciences

RESEARCH INTEREST
Biomaterials, Drug Delivery, Immunology, Nanomedicine, Translational Medicine

Our lab is broadly interested in utilizing high resolution 3D printing to develop novel drug delivery carriers for the treatment of cancer and infectious diseases. Current research interests lay in manufacturing biodegradable porous hydrogel scaffold implants for cell/drug delivery for the treatment of recurrent brain cancer. We are actively investigating biomaterial properties for passive cell/drug loading into scaffolds as well as developing materials and methods to support conjugation strategies for actuated release mechanisms.

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Pharmacology, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Drug Discovery, Pharmacology, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Genetics, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Neurobiology, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Pharmacology, Toxicology, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Translational Medicine

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Immunology, Translational Medicine