Miao, Yinglong
WEBSITE
EMAIL
PUBLICATIONS |
PHD PROGRAM
Bioinformatics & Computational Biology, Pharmacology RESEARCH INTEREST
Aging/Alzheimer's, Biochemistry, Biophysics, Cardiovascular Disease, Computational Biology, Drug Discovery, Pharmacology, Signal Transduction
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Our research is focused on the development of novel theoretical and computational methods and AI techniques, which greatly enhance computer simulations and facilitate simulation analysis, and the application of these methods, making unprecedented contributions to biomolecular modeling and drug discovery. In collaboration with leading experimental groups, we combine complementary simulations and experiments to uncover functional mechanisms and design drugs of important biomolecules, including G-protein-coupled receptors (GPCRs), membrane-embedded proteases, RNA-binding proteins, and RNA. At the interface of computational biology, chemistry, biophysics, bioinformatics and pharmacology, our research aims to address three major topics: (i) development of biomolecular enhanced sampling and AI techniques, (ii) multiscale computational modeling of critical cellular signaling pathways, and (iii) AI-driven drug discovery of medically important proteins and RNA for treatments of neurological disorders, heart failure and cancers.
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Jull, Ellie
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Drug Discovery, Pharmacology, Translational Medicine
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“I am most interested in drug discovery research as it relates to any disease but particularly cancer. I would like to translate my research in vivo to better understand the physiological impact on the disease and how the drug can be improved to reach clinical trials. I have an interest in working towards a certificate in translational medicine too.”
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Bingham, Johnna
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Drug Discovery, Molecular Biology
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“I’m interested in doing research at the intersection of where chemistry and biology meet and using discovery to improve the lives and health of others.”
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Brown, Alex
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Drug Discovery, Pharmacology
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“I am interested in researching the factors that underlie the transition from substance use to abuse, particularly in relation to alcohol. The idea that many people in their lifetimes will consume alcohol but only a relatively small subset of them will later develop problems with alcohol has been a driving question. I aim to study this through the use of rodent behavioral models and in vivo and ex vivo techniques.”
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Binder, Matt
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Chemical Biology, Drug Discovery, Molecular Medicine
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“I would like to use chemical tools to study biological systems and pathways. I am interested in understanding the mechanisms of diseases to find and validate potential drug targets. Hopefully, this knowledge can be used to develop novel therapeutics.”
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González Dalmasy, Jose
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Cancer Biology, Cell Biology, Drug Discovery
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“I am interested in answering questions related to developing better cancer therapeutics. Whether it’s by discovering novel targets and/or using drug delivery approaches to better bioavailability/efficiency of the compounds themselves.”
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Hughes, Jake
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Biophysics, Drug Discovery
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“I am interested in exploring the world of novel protein design and development for a variety of applications including disease and drug discovery, novel synthetic methods and environmental impacts.”
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Fergus, Mary
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Drug Discovery, Pharmacology
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“I am interested in drug discovery for cancer, infections, and other medical diseases. I like investigating how to optimize potential drug treatments. Understanding biochemical pathways to help contribute to drug design.”
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Clarke, Brandon
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Drug Discovery, Neurobiology, Pharmacology
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“I am interested in learning and gaining a better understanding of the molecular basis of neurodegenerative diseases. I’m also interested in gaining a better understanding of drug discovery in the context of diseases such as Alzheimer’s disease, asthma, and pain.”
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Funk, Adam
EMAIL
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PHD PROGRAM
RESEARCH INTEREST
Drug Discovery, Pharmacology, Structural Biology
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“I am interested in using computational drug discovery and structural biology to guide the process of drug discovery and pharmacological characterization of novel drugs. I would like to combine both wet lab techniques and computational analyses to guide my experimental work.”
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