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NameEmailPhD ProgramResearch InterestPublications
Peng, Aimin
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Oral & Craniofacial Biomedicine

RESEARCH INTEREST
Biochemistry, Cancer Biology, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Cell Biology, Cell Cycle, Drug Discovery

Our overarching goal is to delineate how cells respond to cancer therapeutics that induce DNA damage, and, accordingly, to develop new strategies that overcome treatment resistance in cancer, including head and neck cancer. To achieve this goal, we study new mechanisms of the cell cycle and DNA repair using comprehensive experimental systems; we investigate the involvement of these mechanisms in oral cancer progression and resistance; and we develop new therapeutics using cellular, biochemical, and pharmacological approaches.

Pruitt, Kevin
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Pharmacology

RESEARCH INTEREST
Bioinformatics, Cancer Biology, Cancer Genomics, Cell Biology, Cell Signaling, Epigenetics & Chromatin Biology, Immunology, Pharmacology

Pruitt lab research involves 3 broad areas. Interest in the first area (cancer epigenetics) stemmed from discoveries made during postdoctoral training assessing how tumor progression disrupts epigenetic mechanisms of control. The second area (Wnt pathway regulation) was the result of early screens as an Assistant Professor at LSU Health Sciences Center. We uncovered novel regulators of oncogenic Wnt signaling and published the first observation that epigenetic enzymes regulate a critical mediator of Wnt signaling (Dishevelled). The third project involves elucidating mechanisms of aromatase regulation which emerged from the obsession of early trainees in the lab with understanding mechanisms cancer-associated estrogen biosynthesis. Within the context of these three projects, I have mentored and guided multiple trainees at every level over the course of 17 years.

Yates, Melinda

EMAIL
PUBLICATIONS

PHD PROGRAM
Pathobiology & Translational Science

RESEARCH INTEREST
Cancer Biology, Cancer Genomics, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Pharmacology, Toxicology, Translational Medicine

Our translational research lab is focused on the earliest changes that occur in the uterus (endometrium) during cancer development related to obesity and hereditary DNA repair defects. We use preclinical tools (rodents, organoids, and cell lines) to probe mechanisms of endometrial cancer pathogenesis, in parallel with human tissue studies. Our overall goal is to understand how environmental factors, including obesity, hormones, and other exposures, influence endometrial cancer development and disparities so that we can use pharmacologic agents to prevent or reverse cancer development.

Murray, Allison

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Immunology, Molecular Medicine

“I’m interested in exploring mechanisms of adaptive resistance to novel therapeutics, particularly in aggressive tumor models like PDAC, NSCLC, and CRC. I believe that transcriptional rebound mechanisms can be overpowered by the anti-tumor immune system, but the relationships among mechanisms of adaptive resistance and anti-tumor immune system dynamics have yet to be well elucidated. Thus, while I welcome the opportunity to explore both immune cell crosstalk and novel therapeutic efficacy, my hope is to identify a synergistic small-molecule/immunotherapy combo that can not only overcome adaptive resistance to single agent, but also translate well to the clinic.”

Sahoo, Sneha

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Immunology, Translational Medicine

“During graduate school, I would like to work on a cancer biology problem that is heavily translational and multi-disciplinary in nature.

I am really interested in the tumor microenvironment (TME) and I would like to study tumor-promoting/suppressing mechanisms promoted due to cell crosstalk in the TME. Alternatively, I am also interested in studying different molecular mechanisms that result in cancer initiation and metastasis. Ultimately, I would like to utilize my research findings to develop potential therapeutic interventions.”

Griffith, Lauren

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Immunology, Pathogenesis & Infection

“My current research interests are in cancer research, specifically how the microenvironment affects tumor development and progression. I am interested in analyzing how gut microbiota composition can impact disease formation and progression, as well as how genetic factors and mutations can impact it as well.”

Klein, Emma

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Computational Biology, Genomics

“I am most interested in computational biology projects! I aim to combine wet and dry lab, as I would love to be involved in both. Although my past experiences center around cancer genomics, I am open to completely new research areas.”

Armstrong, Emma

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Genomics, Translational Medicine

“I would like to study cancer biology in the translational setting. I am interested in cancer migration and metastasis as well as genomic instability and the tumor microenvironment. In my research I would like to incorporate computational methods as well.”

Bennett, Jack

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Cell Biology, Immunology

“I am interested in understanding the genetics and mechanisms behind cancer formation and progression, evolution and its consequences, signaling pathways involved in developmental biology, the cell cycle, and the immune system. I want to ask questions such as why host genetics can cause a certain infection to be worse or less severe, why some individuals may be more susceptible to certain cancers, what are new ways we can fight cancers and other diseases, or why the cell cycle and associated proteins function the way they do.”

Dawoud, Alyaa

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cancer Biology, Immunology, Molecular Biology

“I am interested in studying cancer immunotherapy as well as the molecular mechanism in cancer, particularly brain cancer.”