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NameEmailPhD ProgramResearch InterestPublications
Livraghi-Butrico, Alessandra
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Microbiology & Immunology

RESEARCH INTEREST
Pathogenesis & Infection, Pulmonary Research, Respiratory Physiology & Infections, Translational Medicine

The Livraghi-Butrico lab is focused on exploring the key determinants of effective airway mucus clearance in health, as well as the consequences of its derangement in muco-obstructive lung diseases. Our lab leverages the unparalleled functional integration offered by in vivo animal models to test mechanistic hypotheses and vet therapeutic options for pre-clinical development.

Rosenthal, Adam
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Microbiology & Immunology

RESEARCH INTEREST
Bacteriology, Molecular Biology, Pathogenesis & Infection, Systems Biology

Our lab uses a systems biology approach to study phenotypic heterogeneity in bacteria. We develop tools that quantify single cell bacterial transcription. We then compare dynamic measurements during vegetative growth and infection to identify regulators of gene expression and mechanisms that bacteria use to coordinate community organization. With this data we want to understand the role of heterogeneity and noise in infectious disease.

Walls, Alex

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Bacteriology, Molecular Biology, Pathogenesis & Infection

Polson, Grace

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Immunology, Pathogenesis & Infection, Virology

Peters, Tiffany

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Pathogenesis & Infection, Pharmacology, Translational Medicine

Pajon, Camryn

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Pathogenesis & Infection, Pathology, Translational Medicine

Huff, Julia

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Immunology, Pathogenesis & Infection, Virology

Dearing, Justin

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Pathogenesis & Infection, Translational Medicine, Virology

Chang, Che Kang

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Immunology, Pathogenesis & Infection, Virology

Thurlow, Lance

EMAIL
PUBLICATIONS

PHD PROGRAM
Microbiology & Immunology

RESEARCH INTEREST
Bacteriology, Cell Signaling, Immunology, Metabolism, Pathogenesis & Infection

By 2035, more than 500 million people worldwide will be diagnosed with diabetes. Individuals with diabetes are prone to frequent and invasive infections that commonly manifest as skin and soft tissue infections (SSTIs). Staphylococcus aureus is the most commonly isolated pathogen from diabetic SSTI. S. aureus is a problematic pathogen that is responsible for tens of thousands of invasive infections and deaths annually in the US. Most S. aureus infections manifest as skin and soft tissue infections (SSTIs) that are usually self-resolving. However, in patients with comorbidities, particularly diabetes, S. aureus SSTIs can disseminate resulting in systemic disease including osteomyelitis, endocarditis and sepsis. The goal of my research is to understand the complex interactions between bacterial pathogens and the host innate immune response with focus on S. aureus and invasive infections associated with diabetes. My research is roughly divided into two project areas in order to understand the contributions of the pathogen and the host response to invasive infections associated with diabetes. Project 1: Defining mechanisms of immune suppression in diabetic infections. Project 2: Determine the role of bacterial metabolism in virulence potential and pathogenesis.