Signal Transduction | Research Interests

Name	Email	PhD Program	Research Interest	Publications
Xi, Gang WEBSITE EMAIL PUBLICATIONS	PHD PROGRAM Cell Biology & Physiology RESEARCH INTEREST Autoimmune Disorders, Biochemistry, Cell Biology, Cell Signaling, Diabetes, Physiology, Signal Transduction, Translational Medicine	My research focuses on signal transduction, proteins posttranslational modification, and protein/protein interaction under varieties of stress/disease conditions. One of my major research areas is vascular smooth muscle signal transduction under hyperglycemic and oxidative stress conditions. Most recently, regulation of vascular smooth muscle cells phenotypic switch under hyperglycemic/uremic conditions was funded by NIH. In addition, I investigate autoantigens that are responsible for autoimmune diseases, such as MCD/FSGS, which make the precise diagnosis and individualized treatment plan possible.
Chen, Gang WEBSITE EMAIL PUBLICATIONS	PHD PROGRAM Cell Biology & Physiology RESEARCH INTEREST Cell Biology, Developmental Biology, Molecular Biology, Molecular Mechanisms of Disease, Pulmonary Research, Regenerative Medicine, Respiratory Physiology & Infections, Signal Transduction, Stem Cells	We use cutting edge technology to study pathogenesis of human pulmonary diseases including cystic fibrosis, Job’s syndrome, idiopathic pulmonary fibrosis by both human specimens, mouse genetic models, with a goal of finding the therapies. Recently, we developed a serial of lung epithelial-lineage tracing systems, providing the powerful tools for identify mechanisms of lung disease involved in post-acute sequelae SARS-CoV-2 infection, also known as “long COVID”, in collaboration with Dr. Ralph Baric’s Lab at UNC-CH.

Name

PhD Program

Research Interest

Publications

RESEARCH INTEREST
Autoimmune Disorders, Biochemistry, Cell Biology, Cell Signaling, Diabetes, Physiology, Signal Transduction, Translational Medicine

My research focuses on signal transduction, proteins posttranslational modification, and protein/protein interaction under varieties of stress/disease conditions. One of my major research areas is vascular smooth muscle signal transduction under hyperglycemic and oxidative stress conditions. Most recently, regulation of vascular smooth muscle cells phenotypic switch under hyperglycemic/uremic conditions was funded by NIH. In addition, I investigate autoantigens that are responsible for autoimmune diseases, such as MCD/FSGS, which make the precise diagnosis and individualized treatment plan possible.

Chen, Gang
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Cell Biology & Physiology

RESEARCH INTEREST
Cell Biology, Developmental Biology, Molecular Biology, Molecular Mechanisms of Disease, Pulmonary Research, Regenerative Medicine, Respiratory Physiology & Infections, Signal Transduction, Stem Cells

We use cutting edge technology to study pathogenesis of human pulmonary diseases including cystic fibrosis, Job’s syndrome, idiopathic pulmonary fibrosis by both human specimens, mouse genetic models, with a goal of finding the therapies. Recently, we developed a serial of lung epithelial-lineage tracing systems, providing the powerful tools for identify mechanisms of lung disease involved in post-acute sequelae SARS-CoV-2 infection, also known as “long COVID”, in collaboration with Dr. Ralph Baric’s Lab at UNC-CH.

Research Interest: Signal Transduction