Cancer Preclinical Models | Research Interests

Name	Email	PhD Program	Research Interest	Publications
Peng, Aimin WEBSITE EMAIL PUBLICATIONS	PHD PROGRAM Cell Biology & Physiology, Oral & Craniofacial Biomedicine, Pathobiology & Translational Science RESEARCH INTEREST Biochemistry, Cancer Biology, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Cell Biology, Cell Cycle, Drug Discovery	Our overarching goal is to delineate how cells respond to cancer therapeutics that induce DNA damage, and, accordingly, to develop new strategies that overcome treatment resistance in cancer, including head and neck cancer. To achieve this goal, we study new mechanisms of the cell cycle and DNA repair using comprehensive experimental systems; we investigate the involvement of these mechanisms in oral cancer progression and resistance; and we develop new therapeutics using cellular, biochemical, and pharmacological approaches.
Yates, Melinda EMAIL PUBLICATIONS	PHD PROGRAM Pathobiology & Translational Science RESEARCH INTEREST Cancer Biology, Cancer Genomics, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Pharmacology, Toxicology, Translational Medicine	Our translational research lab is focused on the earliest changes that occur in the uterus (endometrium) during cancer development related to obesity and hereditary DNA repair defects. We use preclinical tools (rodents, organoids, and cell lines) to probe mechanisms of endometrial cancer pathogenesis, in parallel with human tissue studies. Our overall goal is to understand how environmental factors, including obesity, hormones, and other exposures, influence endometrial cancer development and disparities so that we can use pharmacologic agents to prevent or reverse cancer development.

Name

PhD Program

Research Interest

Publications

PHD PROGRAM
Cell Biology & Physiology, Oral & Craniofacial Biomedicine, Pathobiology & Translational Science

RESEARCH INTEREST
Biochemistry, Cancer Biology, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Cell Biology, Cell Cycle, Drug Discovery

Our overarching goal is to delineate how cells respond to cancer therapeutics that induce DNA damage, and, accordingly, to develop new strategies that overcome treatment resistance in cancer, including head and neck cancer. To achieve this goal, we study new mechanisms of the cell cycle and DNA repair using comprehensive experimental systems; we investigate the involvement of these mechanisms in oral cancer progression and resistance; and we develop new therapeutics using cellular, biochemical, and pharmacological approaches.

Yates, Melinda

EMAIL
PUBLICATIONS

PHD PROGRAM
Pathobiology & Translational Science

RESEARCH INTEREST
Cancer Biology, Cancer Genomics, Cancer Preclinical Models, Cancer Signaling & Biochemistry, Pharmacology, Toxicology, Translational Medicine

Our translational research lab is focused on the earliest changes that occur in the uterus (endometrium) during cancer development related to obesity and hereditary DNA repair defects. We use preclinical tools (rodents, organoids, and cell lines) to probe mechanisms of endometrial cancer pathogenesis, in parallel with human tissue studies. Our overall goal is to understand how environmental factors, including obesity, hormones, and other exposures, influence endometrial cancer development and disparities so that we can use pharmacologic agents to prevent or reverse cancer development.

Research Interest: Cancer Preclinical Models