Do, Jamie
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Biophysics, Chemical Biology
|
“Building on my previous research experience in thiol redox chemistry, enzymology, and protein design, I am eager to delve deeper into the field of macromolecular structure and dynamics as well as chemical biology. For instance, I want to investigate the conformational changes of macromolecules and develop novel small molecule inhibitors for targeted drug delivery. From my current knowledge, the Biochemistry and Biophysics and Pharmaceutical Sciences programs within BBSP will provide the ideal environment for pursuing these research interests. I am also excited about the opportunity to rotate in a lab whose research focus is beyond what I have mentioned.”
|
Reist, Claire
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Immunology, Translational Medicine
|
“I am interested in translational research with a biochemistry/molecular biological approach to understanding mechanisms of disease and identification of potential therapeutic approaches toward treatment. My previous work has focused on airway infection of Cystic Fibrosis and other respiratory diseases. I would like to continue working in a lab whose focus is producing applicable results that directly benefit human health and accelerate the movement of scientific discoveries into clinical practice.”
|
Jimenez, Alli
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Biophysics, Physiology
|
“I am interested in using biochemistry and biophysics to investigate mechanisms underlying certain disease states. In particular, I find the mechanics of protein folding and dynamics to be very intriguing.”
|
Fisher, Caleb
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Bioinformatics, Structural Biology
|
“Broadly, I have an interest in studying enzymology and structural biology to answer questions related to immune and metabolism diseases such as cancer. I think that advancing our understanding of such diseases requires structure-function studies of large protein families, such as GPCRS, to be driven by bioinformatics paired with fundamental biochemistry. A particular question I’m curious about is how the structure of such enzymes contribute to the big-picture of cellular dynamics? More specifically, how does regulation of enzymes change their structural dynamics and how does this fit into the big-picture phenomena of disease?”
|
Fergus, Mary
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Drug Discovery, Pharmacology
|
“I am interested in drug discovery for cancer, infections, and other medical diseases. I like investigating how to optimize potential drug treatments. Understanding biochemical pathways to help contribute to drug design.”
|
Novy, Brandon
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Cell Biology, Structural Biology
|
“My main interests lie in studying dynamic protein complexes through a structural lens. I have really enjoyed investigating the structure/function relationship of proteins implicated in cellular trafficking and am excited to continue studying the molecular architecture of cell biology.”
|
Rice, Ashley
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Immunology, Pharmacology
|
“My research interests involve the use of chemical and molecular biology tools to treat and elucidate disease mechanisms. Specifically, I am interested in developing and characterizing immunomodulatory therapies.”
|
Bridges, Kaitlin
EMAIL
|
PHD PROGRAM
RESEARCH INTEREST
Biochemistry, Computational Biology, Molecular Biology
|
“I am interested in a Biochemistry and molecular biology-focused research group, mostly focusing on RNA. Interested in research that will require performing both wet-lab tasks as well as some computational analysis. Highly interested in a Biochemistry PhD. with a BCB certificate.”
|
Xi, Gang
WEBSITE
EMAIL
PUBLICATIONS |
PHD PROGRAM
Cell Biology & Physiology RESEARCH INTEREST
Autoimmune Disorders, Biochemistry, Cell Biology, Cell Signaling, Diabetes, Physiology, Signal Transduction, Translational Medicine
|
My research focuses on signal transduction, proteins posttranslational modification, and protein/protein interaction under varieties of stress/disease conditions. One of my major research areas is vascular smooth muscle signal transduction under hyperglycemic and oxidative stress conditions. Most recently, regulation of vascular smooth muscle cells phenotypic switch under hyperglycemic/uremic conditions was funded by NIH. In addition, I investigate autoantigens that are responsible for autoimmune diseases, such as MCD/FSGS, which make the precise diagnosis and individualized treatment plan possible.
|
Guardia, Charly
WEBSITE
EMAIL
PUBLICATIONS |
PHD PROGRAM
Cell Biology & Physiology RESEARCH INTEREST
Biochemistry, Cell Biology, Developmental Biology, Developmental Disorders, Disease, Metabolism, Microscopy/Imaging, Molecular Mechanisms of Disease, Physiology, Structural Biology
|
The human placenta is the first organ to develop after fertilization and is the least studied! We hope to change this by using a multidisciplinary approach. From iPSC-derived trophoblasts in culture to mouse models and human placenta tissue, the Placental Cell Biology Group at NIEHS answers fundamental questions about placenta cell and developmental biology. Our lab uses a range of microscopy (cryo-EM, fluorescence), recombinant protein production, and -omics techniques. The goal of our research is to understand how autophagy controls placenta development, differentiation, and function.
|
