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NameEmailPhD ProgramResearch InterestPublications
Lischinsky, Julieta
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Neuroscience

RESEARCH INTEREST
Behavior, Brain Development, Neurobiology, Neurodevelopmental Disorders

Innate social behaviors, including aggression and mating, are crucial for survival and propagation and are therefore shared across species. In the Lischinsky lab we aim to elucidate the developmental, cellular and circuit underpinnings for social behaviors and how these mechanisms are disrupted due to environmental stressors and in neurodevelopmental disorders. We use complimentary tools to study cell identity, function, circuit connectivity, neuromodulation and behavior in the limbic system and beyond during postnatal development, from infancy to adulthood, across sexes.

Balasubramanian, Kavya

EMAIL

PHD PROGRAM

RESEARCH INTEREST
Cell Biology, Neurobiology, Pharmacology

“Broadly, I am interested in the neurobiological mechanisms that differentiate normal and dysregulated circuit function in neurological conditions like substance use disorders and neurodegenerative disease. Specifically, I would like to better understand how intrinsic factors and environmental stressors interact to drive pathological processes in the above conditions.”

Yang, En
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Applied Physical Sciences, Biology, Neuroscience

RESEARCH INTEREST
Brain Development, Computational Biology, Microscopy/Imaging, Neurobiology, Neurodevelopmental Disorders, Neuropharmacology, Quantitative Biology

The EnYang Lab explores interdisciplinary fields to unravel the intricate workings of neural networks within the brain, focusing on how they execute computations, foster imagination, and respond to emotional states. Using larval zebrafish as an animal model, the lab observes, decodes, and perturbs the entire neural networks at single-cell resolution during cognitive tasks. Through the integration of whole-brain imaging, brain-machine interface (BMI), Virtual Reality, optogenetic manipulation, deep learning, and other modern technologies, the lab aims to decipher cognitive abilities in the brain and translate findings into engineering solutions, potentially impacting fields like learning disorders and psychiatric management.

Chen, Jiakun
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Biology, Cell Biology & Physiology, Neuroscience

RESEARCH INTEREST
Brain Development, Cell Biology, Developmental Biology, Genetics, Model Organisms, Neurobiology, Neurodevelopmental Disorders

The goal of our research is to understand how astrocytes develop and how they interact with neural elements during nervous system formation, function, and maintenance. Our lab uses fruit fly Drosophila and zebrafish Danio rerio to explore fundamental aspects of astrocyte biology. We leverage the powerful genetics and unparalleled molecular toolsets in flies to uncover gene function, and we exploit the advanced live-imaging techniques in zebrafish to study astrocyte-neuron interactions in vivo.

Sengupta, Soma
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Neuroscience

RESEARCH INTEREST
Drug Delivery, Drug Discovery, Neurobiology

I am building a career in both clinical and translational research of brain tumors, primary and those resulting from metastasis. Clinically, I primarily see adult brain tumor patients and conduct/initiate clinical trials to meet the needs of this patient population. On the research side, I have a long-standing research interest in clinically-important membrane transport proteins. I conducted genetic and biochemical research on transporters, channels, and pumps during my doctoral research at the University of Cambridge, my postdoctoral study at Yale University, and various institutions (Yale, Johns Hopkins University, Cambridge) while training in medicine at Cambridge. Membrane transport proteins I have worked on include the proton-ATPase (mentor: C. Slayman) and the TAP transporter (mentor: P. Lehner), which are critical to antigen processing. After receiving my medical degree, I pursued advanced medical and additional research training in the U.S. (Johns Hopkins, Harvard) and received continuous funding from the NIH to pursue this research (NINDS-R25, NCI-K12, NINDS-K08). My first independent appointment as an Assistant Professor, Neuro-oncologist was at Emory University in 2016. At the University of Cincinnati, I was the Associate Director of the UC Brain Tumor Center and a recipient of the Harold C. Schott Endowed Chair.

At this time, my lab is focused on: (1) the development of a therapeutic approach for the treatment of primary and pediatric brain tumors, as well as cancers that commonly metastasize to the CNS (lung and melanoma); and (2) translation of technological advances that may impact treatment and quality of life in patients with cancer.

Azizoglu, Berfin
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Cell Biology & Physiology

RESEARCH INTEREST
Cardiovascular Biology, Cell Biology, Developmental Biology, Disease, Neurobiology, Regenerative Medicine, Stem Cells

Our lab studies body-wide control of organ growth and regeneration. The mammalian body is reticulated by blood vessels and neurons. How these networks communicate with organ cells to orchestrate local and body-wide decisions is obscure. We study this question with a focus on the mouse liver, the uniquely regenerative visceral organ. Current projects in the lab include 1-researching the role of a novel vascular progenitor network in liver regeneration, 2-determining the mechanisms of injury perception by liver innervation, and 3-in vitro assembly of reticulated, responsive liver tissue.

Graves, Christina
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Oral & Craniofacial Biomedicine

RESEARCH INTEREST
Gastrointestinal Biology, Immunology, Microscopy/Imaging, Molecular Mechanisms of Disease, Neurobiology, Organismal Biology

Fundamentally, our research is focused on how the nervous and immune systems are developmentally educated by infectious and non-infectious stressors across the “gum-to-gut” axis. One current major focus of the lab is to elucidate how early life stress impacts the developing gut and dentition using zebrafish as an ideal — and translational — model organism. We utilize a combination of advanced imaging, next-generation sequencing, and genetic approaches to achieve a greater understanding of how early life events dictate health outcomes across the lifespan and generations. In addition to these primary research interests, we maintain active collaborations with other groups within the Adams School of Dentistry and across campus.

Khan, Shahzad
WEBSITE
EMAIL
PUBLICATIONS

PHD PROGRAM
Cell Biology & Physiology

RESEARCH INTEREST
Aging/Alzheimer's, Biochemistry, Cell Biology, Molecular Mechanisms of Disease, Neurobiology, Signal Transduction

Maintaining health and reducing disease-risk requires the brain to properly transduce signals across specialized regions and cell types. My lab studies neural signaling at the primary cilium, an antenna-like organelle that helps cells sense and respond to environmental cues. The function of primary cilia in the adult brain remains enigmatic. To probe cilia function, the lab will utilize mouse models, neural cultures, human brain samples, single-cell transcriptomics, proteomics, and microscopy. Ultimately, we aim to identify therapeutic targets for diseases like Alzheimer’s and Parkinson’s.

Vetreno, Ryan

EMAIL
PUBLICATIONS

PHD PROGRAM
Neuroscience, Pharmacology

RESEARCH INTEREST
Addiction/Alcohol Research, Aging/Alzheimer's, Behavior, Biochemistry, Brain Development, Developmental Biology, Disease, Epigenetics & Chromatin Biology, Immunology, Microbiome, Molecular Biology, Molecular Mechanisms of Disease, Neurobiology, Neurodevelopmental Disorders, Neuropharmacology, Pathology, Pharmacology, Regenerative Medicine

My research interests involve investigation of proinflammatory neuroimmune and epigenetic mechanisms in animal models of developmental neurobiology and neurodegeneration, including (1) alcohol pharmacology, (2) alcohol responsivity and tolerance, (3) adolescent neurodevelopment, (4) cholinergic system and neurocircuitry, (5) microglial function, and (6) Alzheimer’s disease. A major focus of the laboratory is elucidation of neuroimmune and epigenetic mechanisms underlying adolescent binge alcohol-induced disruption of basal forebrain cholinergic neurocircuitry in adulthood. A second major focus of the laboratory is investigation of lasting adolescent binge drinking-induced neuroimmune priming as a novel etiological factor contributing to the onset and progression of basal forebrain neuropathology in Alzheimer’s disease. Our laboratory combines ex vivo and in vivo rodent models of alcohol abuse and Alzheimer’s disease with innovative molecular techniques.

Hwang, Janice

EMAIL
PUBLICATIONS

PHD PROGRAM
Cell Biology & Physiology

RESEARCH INTEREST
Aging/Alzheimer's, Diabetes, Human Subjects Research, Medical Imaging, Metabolism, Neurobiology, Physiology, Translational Medicine

My group is interested in understanding the effects of obesity and diabetes on the brain, particularly related to cerebral function and energetics. We conduct physiology based, mechanistic human and rodent studies to investigate fundamental questions such as how does the brain sense various nutrients (sugar, fat, etc), how does metabolic disease, sleep, aging impact brain function and metabolism? Using classic human metabolic techniques including hyperinsulinemic and hyper/hypoglycemic clamps coupled with advanced neuroimaging modalities including 1H and 13C magnetic resonance spectroscopy, functional MRI, and PET-CT imaging, my group has shown that glucose transport capacity into the human brain can be modified by factors such as obesity and insulin resistance as well as hyperglycemia, hypoglycemia and glycemic variability. We also have interests in using novel human imaging modalities to understand how obesity and diabetes impact neuroinflammation and neurodegeneration.