Over millions of years of coexistence humans and pathogens have develop intricate and very intimate relationships. These highly specialized interactions are the basic determinants of pathogenesis and disease progression. Our laboratory is interested in elucidating the molecular basis of disease. Our multidisciplinary approach to molecular medicine is based on our interest in the translation of basic research observations into clinical implementation. For this purpose we use a variety of in vitro and in vivo approaches to study AIDS, Cancer, immunological diseases, gene therapy, etc. Of particular interest is the use of state of the art models such as humanized mice to study human specific pathogens like HIV, EBV, Kaposiâ’s sarcoma, influenza, xenotropic murine leukemia virus-related virus. In addition, we are interested in the development and implementation of novel approaches to prevent viral transmission using pre-expossure prophylaxis and vaccines.