Neurodegenerative disorders like Alzheimer’s disease (AD) represent a global health emergency. Evidence showing that systemic inflammation can exacerbate cognitive decline during neurodegeneration, including AD, and identification of disease-associated genetic risk variants that perturb function of microglia, the resident brain immune … Read more

My research focuses on understanding the immunological underpinnings of autoimmune disease, specifically anti-neutrophil cytoplasmic autoantibody (ANCA) vasculitis. We examine CD4+ T cells in the context of disease onset, remission, relapse, and long-term remission off therapy. By studying both autoreactive T … Read more

Dr. Pew-Thian Yap is a Professor of the Department of Radiology and the Director of the Image Analysis Core of the Biomedical Research Imaging Center (BRIC) at the University of North Carolina at Chapel Hill. He leads a wide range … Read more

The Brain-Spine-Machine Interfaces Lab directed by Dr. Amol Yadav works at the interface of Neuroscience and Engineering. The lab’s goal is to develop neural engineering-based therapies to treat neurological disorders and understand how disorders and injuries impact the brain-spine network … Read more

My research is focuses on two general areas: 1) Molecular principles of auditory information processing, and 2) Gene Therapy approaches to treat neurological disorders. In regard to our auditory focus, we seek to understand how the molecular machinery in auditory … Read more

Our research investigates the effects of air pollutants on maternal health, paternal health, and the health of their children. Through the use of genomics, metabolomics, and proteomics, we investigate the molecular underpinnings of diseases following exposures to pollutants during sensitive … Read more

The Translational and Integrative Sciences Laboratory (TISLab) aims to weave together healthcare systems, basic science research, and patient generated data through development of data integration technologies and innovative data capture strategies. Our research focuses on the development of semantic technologies … Read more

The broad goal in my laboratory is to investigate crosstalk between coagulation and inflammation in animal models of disease. My primary interest is sickle cell disease, a blood disorder caused by a hemoglobin mutation that results in sickling of red … Read more

My lab builds data driven, computational systems to analyze high-resolution histology images of diseased tissue as well as other clinical data sources to improve clinical decision making and advance basic scientific investigation of disease processes. Keywords: Artificial intelligence, computer vision/medical … Read more

Our lab studies molecular interactions between bacteria and the viruses that infect them, called phage. For billions of years, phage and bacteria have been locked in a ‘molecular arms race’. To survive, bacteria have evolved many immune systems to protect … Read more